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NAD+

Is NAD the Same as Vitamin B3?

Georgina Glenn, Registered Nurse October 20th 2025

Is NAD the Same as Vitamin B3?


If you’re interested in health and wellness, or perhaps in search of a supplement to give your body a boost from the inside out, you might have come across both NAD and Vitamin B3. It’s true that both are linked to energy, metabolism and cellular health, but that’s where the similarities end. 

While they are closely related, they certainly aren’t related. Think of Vitamin B3 as the ingredient and NAD (nicotinamide adenine dinucleotide) as the final product that your body creates from it. They do work closely together, and understanding this can help you to understand just why NAD+ supplements are becoming so popular. 

Here, we look at differences between NAD and Vitamin B3, how they’re connected and why directly supporting your NAD+ levels can make a huge difference in how you feel.

What is NAD?

NAD (nicotinamide adenine dinucleotide) is a coenzyme that is found in every living cell. It’s essential for converting the food you eat into energy that your cells can use. It exists in two main forms. NAD+ is the active form, and NADH is the reduced form. The body requires a balance between these two so that its cells can perform efficiently.

Some of the key functions of NAD include:

  • – Energy production: NAD+ helps your cells create ATP, which is the body’s energy currency
  • – DNA repair: It activates enzymes that repair damaged DNA and support longevity and cellular resilience
  • – Metabolic regulation: NAD+ influences metabolism, inflammation and circadian rhythm
  • – Brain and nerve health: NAD+ supports neurotransmitter function and cognitive clarity
  • Without enough NAD+, our cells can’t produce energy efficiently or repair themselves. This is why declining NAD levels are often associated with fatigue, ageing and reduced resilience.

What is Vitamin B3?

Vitamin B3, also known as niacin or niacinamide (nicotinamide), is one of the eight essential B vitamins. It’s commonly found in foods such as chicken, turkey, peanuts, mushrooms and whole grains. Your body uses it to support energy metabolism, maintain healthy skin, nerves, and digestion, and to help with DNA repair and cell signalling. 

Vitamin B3 is water-soluble, which means it isn’t stored in large amounts in the body. This is why regular intake, whether through food or supplements, is essential for overall health.

Is Glutathione or NAD+ Better?
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How Vitamin B3 Relates to NAD Production

Vitamin B3 acts as a precursor to NAD, meaning your body uses B3 to make NAD. What’s more, there are three main forms of B3 that can contribute to this process: 

  1. Niacin (nicotinic acid)
  2. Niacinamide (nicotinamide)
  3. Nicotinamide riboside (NR)

Each enters the body either through diet or supplementation and is then converted through enzymatic pathways into NAD. In short, vitamin B3 enters your body and then, after several conversion steps, NAD+ comes out the other end.

This process is a natural one that works efficiently in youth but typically slows down with age and metabolic stress, leading to lower NAD+ levels even if your B3 intake remains steady.

Is NAD the Same as Vitamin B3?

While the two are connected, they are not the same.

Vitamin B3 is a nutrient that your body obtains from food or supplements. NAD+ coenzyme is a compound that your body produces from that nutrient. For example, think of B3 as the flour and NAD+ as the bread. You need the ingredient to make the final product, but the effects of consuming one are not identical to having enough of the other.

That’s why taking Vitamin B3 doesn’t always result in optimal NAD+ levels, especially as we age!

Why NAD Levels Decline With Age Despite B3 Intake 

You might think that eating enough B3 should keep your NAD levels high. But research shows that NAD+ levels naturally decline with age, often by as much as 50% between early adulthood and middle age. This happens for several reasons:

  • – Reduced conversion efficiency: The enzymes that convert B3 into NAD become less active with age.
  • – Increased NAD consumption: Chronic inflammation, oxidative stress, and DNA damage deplete NAD reserves faster.
  • – Cellular stress: Environmental toxins, poor sleep and metabolic disorders accelerate NAD breakdown.

This means that, unfortunately, even a balanced diet can’t always maintain optimal NAD levels – leaving cells with less energy for repair, detoxification and function. This is just one reason why NAD+ supplements have gained attention as they bypass the body’s declining conversion efficiency and restore NAD levels directly.

The role of NAD+ Therapy Compared to Dietary Intake

Eating foods rich in B3 or taking niacin/niacinamide supplements is one of the best ways to support overall nutrition and basic NAD production in the body. However, this approach does depend on the body’s ability to convert B3 efficiently, something that is slowed down with age, illness or chronic stress.

This is why more people are turning to NAD+ AT HOME supplements to deliver the coenzyme directly into the bloodstream, making it available for immediate cellular use.

This approach avoids the conversion bottleneck and rapidly replenishes depleted NAD stores.

Some benefits of consistent NAD+ supplementation may include: 

  • – Improved energy and reduced fatigue
  • – Enhanced focus and mental clarity
  • – Better recovery from exercise or stress
  • – Support for healthy ageing and metabolic function

Supporting Health With NAD+

Remember, vitamin B3 and NAD are closely related, but they aren’t the same!

Vitamin B3 is the ingredient that your body uses to make NAD, and NAD+ is the active coenzyme that fuels cellular energy and repair. As we age, natural NAD production declines even when B3 intake remains high. This is where NAD+ AT HOME comes in, restoring NAD levels more directly, helping your body perform at its best.

Want to support your health beyond diet alone? Explore our range of NAD+ products and discover how we can help boost your energy, focus, and overall vitality.

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