If you’ve been paying attention to the wellness space lately, it’s hard to miss how often GLP-1 medications like Ozempic and Mounjaro are being talked about recently.
For many people, these medications have been genuinely life-changing. Appetite reduces, and portions shrink naturally. Eating feels calmer and more neutral. Weight loss becomes possible without feeling like it’s a daily battle.
People are losing weight, but they’re also asking how to support their bodies while doing it. That’s where NAD+ keeps coming up.
This article will explore how NAD and GLP-1 medications work, why they’re often used together, and how NAD helps with supporting your energy, wellbeing and resilience during weight loss.
Key Takeaways of this Article:
- – GLP-1 medications help reduce appetite and food noise
- – NAD supports cellular energy, repair and resilience
- – They work in completely different ways
- – Many people use NAD and GLP-1 to feel less drained and more supported during weight loss
What GLP-1 Medications Do (and What They Don’t)
GLP-1 medications work mostly through the gut and brain. They do this by slowing digestion, reducing appetite and helping people feel full much sooner than they would have before.
What they don’t do is directly support the body’s energy systems, cellular repair or recovery.
When you’re eating much less food than before, your body still has the same daily demands. It still needs to fuel your brain, repair tissues, keep hormones balanced, support your immune system and allow you to move and exercise. It just has fewer incoming calories to work with.
Weight loss, especially when it’s rapid or sustained, is still a form of physical stress. Even when it’s wanted. That’s why some people are surprised by how they feel once the scales start moving!
When Weight Loss Feels Harder Than Expected
For some people, weight loss comes with feeling more tired, a low mood or a sense of feeling just a bit flat. Motivation dips and exercise all of a sudden feels harder. There can be a sense of “oh should feel great, but I don’t”.
When calorie intake drops significantly, the body still has to:
- – Fuel the brain and nervous system
– Repair muscles and tissues
– Maintain hormone balance
– Support immune function
– Allow you to move, exercise and recover
The difference is that it now has less fuel coming in to do all of this. This is why some people feel surprised by how they feel during weight loss, even when it’s going well.
Hair shedding, duller skin, weaker nails can occur when taking GLP-1 medications.
These things can feel worrying, but they’re often signs that the body is under pressure rather than something going wrong. Hair, skin and nails are tissues that regenerate quickly, so they’re often the first to reflect internal strain. When energy intake drops, the body prioritises essential systems first.
This is where NAD plays a very different role from GLP-1 medications.
NAD: Supporting the Body at a Cellular Level
NAD is not a stimulant or a trend ingredient. it’s a molecule found in every single one of our living cells, and it’s absolutely essential for how the body produces energy and repairs itself.
Every time your body creates energy, repairs damage or responds to stress, NAD is involved.
The challenge is that (if you’re a regular on our blog, you’ll know this already!) NAD levels will naturally decline as we age. They can also drop more quickly during periods of physical stress which can be anything from illness, intense training, poor sleep and calorie restriction.
When NAD levels are low, people often describe feeling drained, foggy or less resilient. Not ill, just not quite themselves.
Supporting NAD doesn’t force energy or override the body’s signals. Instead it can help the body work more efficiently with the resources it has available.
Can You Take NAD and GLP-1 Together?
Yes, and they often are taken together!
GLP-1 medications influence how much you eat, and NAD supports how your body copes with eating less. They work through completely different mechanisms, which is why many people find them complementary rather than overlapping.
We often hear that NAD doesn’t affect appetite at all, and that’s the point. What they notice instead is how they feel day to day. More mentally clear and less wiped out.
More able to stay active and engaged with life whilst their weight changes. And rather than pushing the body harder, NAD will help it better cope with the changes already underway.
What People Notice When Using NAD With GLP-1 Medications
NAD helps convert food into energy, but what it doesn’t do is suppress appetite and it isn’t meant to. Instead, people commonly report changes in how they feel day to day, such as:
- – Feeling less tired
– Improved mental clarity
– Better ability to stay active
– Less of a flat or depleted feeling
Rather than accelerating weight loss, NAD supports the experience of weight loss.
Energy, Motivation and Staying Active
One of the biggest concerns people raise during weight loss is energy. Not just physical tiredness, but a lack of drive or motivation.
Movement matters more than calorie burn. It supports mood, muscle mass, bone health and long-term metabolic health. But it’s hard to stay active if you feel constantly exhausted.
Many people using NAD alongside GLP-1 medications may feel less flat and more capable of moving their bodies. That might mean returning to gentle exercise, walking more, or simply feeling able to get through the day without crashing.
It’s about feeling supported rather than depleted.
Hair, Skin and Nails as Signs of Internal Support
Changes in hair, skin and nails can be unsettling, especially when you’re doing something positive for your health. What’s important to understand is that these tissues often reflect what’s happening internally. When the body is under strain, it may divert resources away from what the body classifies as non-essential systems.
Many people using NAD whilst taking GLP-1 medications notice much better skin resilience, less hair shedding and stronger nails over time. These aren’t cosmetic promises. There are often signs that the body is managing the transition more smoothly at a cellular level.
Not a Replacement. But Definitely a Supportive Layer!
NAD is not a substitute for GLP-1 medications, but what it does do is support the systems that still need to function well while weight loss is happening.
That’s why this pairing feels intuitive to so many people. One approach reduces intake. The other helps the body adapt to that reduction without feeling constantly run down.
Different roles. Shared goal.
Explore NAD+ AT HOME Products Today
At NAD+ AT HOME, we’ve focused on making NAD support accessible, safe and convenient, with options including injection kits, injection pens, liposomal capsules and L-Glutathione support.
If you’re using prescription medication, always speak with your healthcare professional about what’s right for you!
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