Nicknamed the molecule of youth, NAD+ is a coenzyme found in every single cell in your body. It plays a big role in:
- – Converting your food into cellular energy.
- – Repairing your DNA.
- – Supporting your brain and nervous system health.
- – Activating your sirtuins (your longevity genes).
- – Slowing the ageing process at the cellular level.
But, as you’ll already know by now (if you’re a loyal NAD+ AT HOME blog reader), your NAD+ levels naturally decline as you age. By the time you hit roughly your 40s, your levels can be just half of what they were in your 20s. This decline is linked to fatigue, sluggish metabolism, brain fog, reduced skin elasticity, and increased risk of age-related diseases.
So how do you restore NAD+ and stay you? Energised, and glowing from the inside out? This blog explores boosting NAD+ levels naturally.
Quick Overview: Why NAD+ Declines with Age
NAD+ is essential for your mitochondria – the energy powerhouses of your cells. Without enough NAD+, your body can’t produce energy efficiently, nor can it repair itself at the cellular level.
Ageing, stress, inflammation, environmental toxins, poor diet, and lack of sleep all accelerate NAD+ depletion. That’s why by mid-life, most of us feel the difference – physically, mentally, emotionally.
But here’s the good news: you can naturally support your body’s ability to produce more NAD+ with a few key lifestyle tweaks, evidence-based tools, and targeted supplements.
1. Use NAD+ Precursors (Yes, They Work If You Pick the Right Ones)
You may have heard that taking NAD+ directly doesn’t work well, and that’s mostly true. The NAD+ molecule is large and unstable, meaning it’s not easily absorbed by the body when taken orally.
Instead, the smarter approach is to use precursors, compounds your body uses to make its own NAD+.
The top NAD+ precursors to know:
- – NMN (Nicotinamide Mononucleotide)
- – NR (Nicotinamide Riboside)
Both have been widely studied and shown to support healthy NAD+ production, especially when combined with other synergistic compounds.
- – Pro tip: Look for formulations that also support NAD+ recycling, such as TMG (trimethylglycine), quercetin, or resveratrol.
- – Bonus tip: Some advanced supplements, like our in-house NAD+ Injection Pen Kits, bypass the gut entirely, delivering NAD+ subcutaneously for maximum absorption (more on that later).


2. Intermittent Fasting
Although not suitable for everyone, fasting can be one of the most powerful ways to support your cellular health and NAD+ production.
When you fast, your body initiates a process called autophagy, where it clears out damaged cells and regenerates healthier ones. This process increases the activity of sirtuins, which are directly activated by NAD+. The result is that your cells can become more efficient, resilient, and youthful.
You don’t need to go extreme. Consistency beats intensity when it comes to fasting benefits – and remember to talk to your doctor before trying intermittent fasting.
3. Move Your Body (Especially With HIIT or Resistance Training)
Exercise is one of the most potent natural boosters of NAD+ levels. Why? Because when your muscles contract, they demand energy, and that demand signals your cells to produce more NAD+.
Best Types of Exercise for NAD+ Production
- – High-Intensity Interval Training (HIIT): Short bursts of intense effort, followed by rest.
- – Resistance training: Lifting weights or bodyweight exercises.
- – Steady cardio: Walking, cycling, swimming.
- – Pilates: Low-impact but still boosts circulation and metabolic health.
Aiming for a mix of all of these is great, but most importantly, find something you’ll actually stick to. Movement leads to better mitochondrial health, which leads to more NAD+.


4. Saunas & Cold Exposure
Hormesis is the concept of good stress. So, small, controlled stressors that trigger your body to adapt and become stronger. Both heat and cold are fantastic hormetic tools for boosting NAD+ levels.
Infrared Saunas or Hot Baths
- Increase heat shock proteins that promote protein folding and cellular protection.
- Support mitochondrial function and NAD+ recycling.
Cold Showers or Ice Baths
- These activate AMPK, which is a key regulator of energy balance and NAD+ production.
- Increase mitochondrial biogenesis (which means more energy-producing organelles).
Even 2 to 3 sessions per week of hot or cold exposure can help!


5. Reduce Inflammation, Toxins, and Poor Sleep
Your body loses NAD+ through certain enzymes like CD38, which are activated by inflammation, oxidative stress, and poor lifestyle habits.
So, to preserve your NAD+ stores, you need to look at ways to minimise toxins, inflammation and work on a better sleep routine.
How to Focus On Anti-Inflammatory Living
- – Support your liver and detox pathways.
- – Eat more leafy greens, oily fish, turmeric, berries, olive oil, and nuts.
- – Limit sugar, processed foods, and alcohol.
- – Prioritise sleep. Even mild sleep deprivation depletes NAD+.
- – Supplements could be worth it if your levels are low to begin with. For example, Omega-3s may reduce inflammation, and magnesium supports mitochondrial function.
- – Manage stress with breathwork, journaling, or mindful movement.


6. Biohacking: NAD+ Injection Pens
While natural lifestyle strategies are essential, some people want faster, more measurable results.
That’s where NAD+ Injection Pens come in. Unlike traditional NAD+ drips (which require clinic visits, time off, and often a hefty price tag), our needle-free, subcutaneous pens offer the same cellular benefits in under 60 seconds.
Benefits of the NAD+ Injection Pen:
- – Painless, at-home delivery.
- – Higher bioavailability than capsules.
- – Fast onset of energy and clarity.
- – No messy measuring or clinic visits.
- – Pre-filled cartridges for precision dosing.
It’s modern wellness made effortless, ideal for anyone looking to feel better, sharper, and stronger.


Final Thoughts: Boosting NAD+ Naturally Is the Smartest Move You Can Make
Whether you’re in your 30s and want to start your health journey, or in your 50s and feeling the energy dip, NAD+ deserves a place in your wellness routine.
From smart supplementation and fasting to saunas and sleep, every small choice you make can contribute to higher NAD+ levels, and that means more energy, resilience, and vitality to do the things you love.
And for those who want more precise control? Our NAD+ Injection Pen is a game changer.
Ready to Level Up Your Energy and Longevity?
Our NAD+ Injection Pen Kits are designed to help you take charge of your health at home – zero appointments, no hassle, just pure cellular support. Travel-friendly, designed for daily or weekly use and backed by science, trusted by professionals
Explore the NAD+ Injection Pens. Your future self will thank you!
Disclaimer
Everyone’s health journey is unique. The information shared here is for general wellness purposes only and shouldn’t replace personalised medical advice. If you have any health conditions, are pregnant or breastfeeding, or are on medication, please be sure to check in with your doctor before making changes to your routine!