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A Guide to L-Glutathione: The Antioxidant You Need to Know About

If you’ve been hearing more about L-glutathione lately, you’re not alone. This powerful antioxidant is gaining attention for its role in detoxification, immune support, and overall health. But what exactly makes L-glutathione so important, and how can it benefit you?

In this article, we’ll be covering exactly what L-glutathione is, how it works within your body, and why it’s key in supporting your health.

Whether you’re looking to boost your levels naturally or find the right supplements, we’ve got you covered. Plus, we’ve also left room to answer some of the most common questions about L-glutathione, so keep reading to find out everything you need to know.

What is L-Glutathione?

L-glutathione is a powerful antioxidant. And it’s actually (naturally) found in every cell of the body, made up of three amino acids – glutamine, cysteine, and glycine. 

This antioxidant plays an essential role in protecting the body from oxidative stress and free radical damage, which can otherwise lead to cellular damage. 

Although L-glutathione is produced by our bodies naturally, many things can disrupt its production. This includes:

  • Poor diet.
  • Stress.
  • Natural ageing.
  • Environmental toxins.
  • Some medications. 
  • Exercise that’s on the more intense side.

This is why maintaining adequate levels of this crucial antioxidant is so essential for overall health.

What is L-Glutathione?

What Does L-Glutathione Actually Do in the Body?

L-glutathione’s most important role in our bodies is to neutralise harmful free radicals and reactive oxygen species that can damage cells. For those who don’t know, free radicals are basically unstable molecules that cause oxidative stress, speeding up ageing and contributing to things such as our susceptibility to inflammation and disease. L-glutathione helps keep them in check, protecting our cells and supporting our immune systems along the way.

So, just to recap the above, here’s what L-glut does in the body:

✔ Helps us detox: L-glutathione helps detoxify the liver by binding to toxins and heavy metals for easier elimination.

✔ Provides immune system support: It helps regulate white blood cell activity, boost immune function, and protect against illness.

✔ Enhances antioxidant protection: L-Glutathione neutralises free radicals, reducing inflammation and protecting against oxidative damage.

✔ Improves overall skin health: It may help reduce the appearance of wrinkles, fine lines, and dark spots by fighting oxidative stress and improving skin tone.

✔ Protects our brain function: L-Glutathione protects the brain from oxidative stress, supporting cognitive health and even potentially preventing neurodegenerative diseases.

What Does L-Glutathione Actually Do in the Body?

Why Do Our L-Glutathione Levels Decline?

Our l-glutathione levels can decline for many reasons, but the main one is ageing. As we age, our bodies just naturally produce less L-glutathione. 

Other factors can also accelerate the depletion, which include:

A consistently poor diet lacking essential nutrients. Especially if you’re lacking in vitamins that support antioxidant production (such as vitamins C and E).

✘ Living in a state of prolonged stress increases oxidative stress in the body, which may also lead to a faster depletion of L-glutathione.

Exposure to pollution, chemicals, and heavy metals can all drain l-glutathione reserves in the body.

Alcohol can damage the liver, which in turn affects the body’s ability to produce and recycle L-glutathione.

What Are the Key Benefits of L-Glutathione?

Making sure your body has the right L-glutathione levels can offer a wide range of health benefits.

Below, we’ve listed some of the most well-known advantages associated with l-glutathione.

What Are the Key Benefits of L-Glutathione?

Anti-ageing and Skin Health Benefits

L-glutathione helps protect the skin by reducing damage from free radicals and inflammation. For this reason, it’s linked with making our skin look glowy and lightening dark spots, with some even reporting wrinkles appearing less pronounced when taking a supplement, leaving your skin looking younger and more radiant.

A Boost to Energy Levels

L-glutathione supports the body’s detox processes and reduces oxidative stress, which can help increase energy levels and reduce how tired we feel day-to-day. 

Many people report feeling more awake and energised after using a supplement for some time. In fact, it’s described as more energising than caffeine. 

Helps With Detoxing

L-glutathione is known to be essential for the liver. It helps with removing all of the toxins we accumulate from the body. So, making sure we’re keeping levels of L-glutathione in a healthy place supports liver function and helps eliminate harmful substances more efficiently.

Supports Healthier Cognitive Function

  • Our ability to hold and maintain focus.
  • How sharp our memory is.
  • Overall mental clarity
  • Reducing the risk of cognitive decline as we age.

Promotes Strong Immune Health

Many studies have researched healthy l-glutathione levels and how this positively impacts our immune system, with a positive link being a common conclusion.

According to multiple studies, L-glutathione plays a key role in keeping the immune system functioning well. It helps regulate immune cells and supports the body’s ability to fight off infections, making it essential for overall immune health.

glutathione injection supplement vials laying flat birdseyeview on blue background

What’s the Best Type of L-Glutathione Supplement?

Just like most supplements, when looking at ways to boost l-glutathione levels effectively, how you choose to do that really matters. 

There are plenty of options on the wellness market, but the better quality options are injectable forms. This delivers the antioxidant directly into your bloodstream, bypassing the digestive system entirely – which means your body can absorb it much more efficiently and feel the benefits faster. 

Injectable L-glutathione is especially great for people looking for a quick boost in energy, detox, or skin health. 

Commonly Asked Questions About L-Glutathione

Does l-glutamine Increase Glutathione​?

Yes! L-glutamine can help boost glutathione levels indirectly. It provides the body with some of the building blocks needed to produce glutathione, but it’s not the same as directly taking L-glutathione.

Is l-Glutathione Safe​?

Yes, L-glutathione supplements are generally safe for most people when taken in the recommended amounts. However, as with any supplement, it’s best to check with a healthcare provider, especially if you have any existing health conditions or are on medication!

What Is the Role of Glutathione As An Antioxidant?


Glutathione helps protect the body’s cells from damage caused by free radicals and oxidative stress. It neutralises harmful molecules that can cause inflammation, ageing, and disease, which makes it one of the body’s key antioxidants.

How Can You Boost L-Glutathione Levels Naturally?

As we touched on earlier in this article, your body makes L-glutathione naturally. However, if levels are depleting for whatever reason and you’re not looking for supplements, there may be several simple ways to boost your levels through diet and lifestyle. 

Eating foods rich in glutathione or that help your body produce it is a great start. Garlic, spinach, avocados, broccoli, and kale can all be excellent choices. Exercise is another big one, too – as it helps improve your body’s ability to produce glutathione while reducing oxidative stress. 

Getting enough sleep helps with many things, and L-glutathione levels are no exception. It supports detox and cell repair, both of which rely on healthy glutathione levels. Also, cutting back on alcohol may also help preserve your glutathione and protect your cells.

How Do NAD+ and Glutathione Differ in Supporting Cellular Health?

NAD+ and glutathione share similar benefits for improved cellular health, but differ slightly in their main functions. Despite both promoting improvement for overall health and wellbeing,  NAD+ supports cellular energy production, whilst L-glutathione is transformative for detoxification and skincare. 

NAD+ is a coenzyme for energy production and DNA repair, which has a role in cellular metabolism and longevity. Glutathione, on the other hand, is an antioxidant that’s focused on protecting cells from oxidative stress and supporting detoxification processes. 

So, for example, you might choose to start a NAD+ supplement if they’re focusing on boosting energy levels, improving metabolic function, or addressing age-related cellular decline. 

If you’re more concerned with improving the overall appearance of your skin, enhancing your body’s antioxidant defences, supporting liver health, or combating the effects of environmental toxins, an L-glutathione supplementation would definitely be a better option.

Should You Boost Your L-Glutathione Levels?

If you’re looking to improve your overall health, support immune function, or slow down the ageing process, boosting your L-Glutathione levels can have a significant impact. 

Whether that’s through making lifestyle changes or choosing a high-quality supplement, ensuring that your body has enough of this powerful antioxidant is a great way to improve your overall health.

If you’re ready to enhance your well-being and prepared to discover the benefits, take a closer look at our L-glutathione supplement today. Alternatively, if you have queries about taking a supplement, we encourage you to get in touch with our team today.