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NAD+

Can NAD+ Help With Weight Loss?

Georgina Glenn, Registered Nurse October 31st 2025

Can NAD+ Help With Weight Loss?


For many people, achieving and maintaining a healthy weight can feel like a constant battle. So, can NAD+ help with weight loss?

Busy lifestyles, stress and the natural slowing of metabolism with age can make it feel like you’re stuck in a rut – even when positive changes are being made. That’s why more people are exploring complementary options that support their body through energy, metabolism and motivation. One such solution is NAD+ therapy

In recent years, NAD+ has gained attention for its ability to boost cellular energy and support metabolic health. And while it’s not an all-in-one solution for shedding the pounds, it can play a vital role in supporting well-rounded weight management.

The Role of NAD+ in Metabolism

NAD+, short for nicotinamide adenine dinucleotide, is found in every living cell in the body. It plays an important role in turning food into energy by helping the body to convert ATP (adenosine triphosphate). Unfortunately, though, as NAD+ levels decline with age and stress, this energy conversion becomes less efficient. 

This then results in fatigue, reduced calorie burning and a bigger challenge of maintaining a healthy weight. But by supporting NAD+ levels, either through IV therapy, supplements or lifestyle changes, the body may be able to process food more effectively and utilise stored fat as energy. 

Research is still in its early stages, but current studies do suggest that boosting NAD+ may enhance mitochondrial function and improve metabolic flexibility. In short, this means the body can switch more easily between burning carbohydrates and fats for fuel.

Can NAD+ Help With Weight Loss? A woman in pilates class
Can NAD+ Help With Weight Loss? A woman running.

How NAD+ Supports Energy for Physical Activity

We’re regularly told that consistent exercise is one of the best ways to lose weight and manage it healthily. But if you suffer from fatigue, this may be a challenge. NAD+ is essential for cellular energy production, so increasing it is one way to reduce tiredness and improve endurance. 

What’s more, when your cells are functioning efficiently, muscles can recover faster, and you’re more likely to sustain your workouts. This added energy can make physical activity feel more manageable, which can do wonders for consistency and, therefore, long-term results.

Some users of NAD+ therapy even report feeling more focused as well as energetic, which again can translate into improved motivation for movement and healthier daily choices. It’s important to note that personal experiences will vary, but enhanced stamina and reduced fatigue are among the most commonly reported benefits of NAD+ support.

NAD+ and Appetite Regulation

As well as energy metabolism, NAD+ also plays a role in cellular communication and hormone regulation. This has a part in appetite and satiety. NAD+ in involved in the pathways that affect neurotransmitters like serotonin and dopamine, which can influence mood and cravings.

There’s also evidence that NAD+ can interact with the brain’s signalling molecules related to hunger. However, more research is needed. For now though, we can say that NAD+ can be supportive in stabilising energy levels. This in turn can make it easier to manage appetite and resist emotional eating, rather than it being used as a direct appetite suppressant.

The Connection Between Ageing, NAD+ Decline, and Weight Gain

As we age, natural levels of NAD+ start to decline – sometimes by as much as 50% by middle age. This can result in slower metabolism, reduced energy output and an increased tendency to store fat rather than burn it.

At the same time, hormonal changes and lower activity levels often make weight management even more difficult. But supporting NAD+ levels through therapy may help counteract some of these effects. 

What’s more, NAD+ therapy has also been linked to improved mitochondrial function, which may help the body use nutrients more effectively and reduce oxidative stress. These are both crucial for a healthy weight as you age.

Can NAD+ Alone Cause Weight Loss?

It’s important to note that NAD+ is not a standalone weight-loss solution. However, research shows that increasing NAD+ levels can support metabolism and energy production, which are essential for healthy weight management. Lasting results will come from a combination of healthy eating, regular exercise, good sleep and stress management.

Instead, NAD+ can be viewed as the foundation that helps your body to perform at its best. When paired with positive habits, it can boost results by improving energy, focus and recovery. But without the right lifestyle approach, NAD+ on its own won’t create significant or sustainable fat loss.

Other Proven Strategies for Healthy Weight Management

For those looking to lose weight healthily and for the long run, there are various evidence-based approaches to follow. This includes:

  • – A nutritious diet: Focus on whole foods, lean proteins and fibre. 
  • – Regular movement: Combine cardio, strength training and daily activity to boost metabolism.
  • – Sleep and stress management: Poor sleep and chronic stress can disrupt hormones that regulate hunger and fat storage.
  • – Hydration: Adequate water intake supports digestion, energy and satiety.

By using NAD+ therapy, alongside the above proven techniques, you can create an environment that supports a healthy and happy mind, as well as effective weight management.

How NAD+ At Home Can Support Your Weight Loss Journey 

NAD+ At Home makes it easier for you to experience the benefits of NAD+ therapy in a safe and convenient setting. From the comfort of your home, you can receive professional-grade NAD+ treatments with expert support throughout the process.

Whether you’re looking to enhance energy, improve recovery or complement your weight loss plan, each session is personalised and designed to deliver consistent results. What’s more, for those with busy schedules, at-home therapy offers a practical way to integrate NAD+ support into a holistic health routine.

Support Your Long-Term Health and Energy

NAD+ isn’t a quick fix but it can be an effective tool in your journey to better health and weight management. So, if you’re ready to explore how NAD+ therapy can help you feel more energised and motivated in your weight loss journey, consider starting with NAD+ At Home.

Want to see how NAD+ therapy can support your energy and health goals? Learn more with NAD+ At Home.

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