A Complete Guide to NAD+ Injections

You may have encountered references to NAD+ injections but remain uncertain about their potential benefits or the specifics of the procedure.

This comprehensive guide aims to provide detailed information about NAD+ and how at-home NAD+ injections may contribute to enhancing your overall wellbeing.

Understanding NAD+

NAD (or nicotinamide adenine dinucleotide) is an essential coenzyme found in every living cell.

It is involved in several vital processes, including:

NAD+ is the oxidised form of nicotinamide adenine dinucleotide (NAD) and is available as an injectable supplement for at-home use. It is a critical coenzyme involved in cellular metabolism, facilitating the production of ATP, the primary cellular energy molecule of the cell.

NAD+ also serves as a necessary cofactor for sirtuins, enzymes that regulate DNA repair, genomic stability, and the modulation of ageing-related pathways.

Levels of NAD+ decline naturally with age and can be influenced by various factors, including oxidative stress, inflammation, and lifestyle choices, all of which may impact overall cellular function and health.

Why NAD+ Levels Decline Over Time

NAD+ levels naturally decline as we age. Research analysing tissue samples has shown that NAD+ concentrations in organs decrease with advancing age, and this decline is linked to increased activity of enzymes that consume NAD+ (for example, CD38) in older individuals.

This age-related decline can be further accelerated by factors including oxidative stress, DNA damage, and chronic inflammation.

While maintaining a healthy diet and lifestyle can support your body’s natural ability to produce NAD+, these measures may not always fully counteract the age-related decrease.

NAD+ injections provide a safe and convenient way to boost NAD+ levels and support cellular health. Although emerging evidence shows promising effects on energy metabolism and cellular function, ongoing research continues to explore the full extent of the clinical benefits.

How NAD+ Injections Work in the Body

NAD+ injections involve the administration of sterile NAD+ solutions directly into the body. Traditionally, this procedure required attendance at a medical facility for intravenous or intramuscular injections.

More recently, NAD+ can be delivered subcutaneously using injector pens. These devices operate similarly to insulin pens, providing a convenient and minimally invasive option for at-home use.

This method enhances the bioavailability of NAD+ by bypassing the digestive system, thereby offering a more effective alternative to oral supplementation.

Using an at-home injection pen, NAD+ is delivered directly into the bloodstream. Unlike oral supplements, which undergo partial breakdown during digestion, this method ensures a significantly higher amount of NAD+ reaches systemic circulation.

NAD+ injections can achieve nearly 100% bioavailability, the proportion of an active substance that enters the bloodstream and is available for use.

Potential Benefits of NAD+ Injections

NAD+ injections have been associated with a range of potential benefits, primarily through their role in enhancing cellular energy metabolism. By elevating NAD+ levels, these injections may improve mitochondrial function, which can lead to increased cellular energy production and reduced feelings of fatigue.

Emerging research suggests that NAD+ may also support genomic stability and DNA repair processes, which are critical for maintaining cellular health and promoting healthy ageing.

Additionally, NAD+ is involved in activating sirtuins, enzymes that regulate inflammation, oxidative stress, and metabolic homeostasis.

Potential benefits of NAD+ supplementation include improved cognitive function and mental clarity, enhanced metabolic health, and support for skin health by influencing cellular repair mechanisms.

It is important to note that while these benefits are promising, they remain potential effects under ongoing scientific investigation.

NAD+ Injections vs Other NAD+ Delivery Methods

There are several ways of taking NAD+ supplements, including:

Oral NAD+ Supplements

Oral NAD+ supplements provide a convenient means to support NAD+ levels and are particularly suited for individuals who prefer to avoid injections.

Although their bioavailability is generally lower compared to injections, our liposomal NAD+ capsules are formulated to enhance absorption and maintain a high level of efficacy.

IV NAD Therapy

This method delivers NAD+ directly into the bloodstream through an intravenous (IV) drip. It is highly effective in terms of absorption but is typically the least convenient and most costly option.

Treatment usually requires a visit to a clinic or medical facility. During NAD+ treatment, some individuals may experience side effects such as flushing or redness at the injection site, mild pain or discomfort during administration, nausea, or an upset stomach.

Other reported effects include headaches, fatigue, dizziness, muscle cramps, and a general feeling of light-headedness or warmth. These reactions are generally mild and temporary but should be monitored for safety.

At-Home NAD+ Injections

At-home NAD+ injections offer an optimal balance of convenience and efficacy, delivering high bioavailability through a straightforward and easy-to-use injector pen.
NAD+ injections are generally considered very safe when administered properly.

Our NAD+ pens provide precise dosing and should be used strictly according to instructions. It is essential to use sterile, single-use equipment to minimise risk.

The 8mm micro-needles are specifically designed to reduce the likelihood of needle-related injuries; however, maintaining proper hygiene and following appropriate sharps disposal protocols remain crucial.

Who Should NOT Use NAD+ Injections

NAD+ isn’t suitable for those under 18 years old or with any of the following health conditions and contraindications:

What Is an At-Home NAD+ Injection Kit?

Ease of use and safety are both essential to our NAD+ AT HOME injection kit. Each kit contains everything you need to deliver your own NAD+ injection safely at home, including:

• NAD+ vial or NAD⁺ cartridges for auto-injector pen

• Instructions + video access

• Micro-needles or an auto-injector pen

• Alcohol wipes

• Sharps bin

Common Questions About NAD+ Injections

Do NAD+ Injections Hurt?

The injection can sting and may cause a bruise, but most people find that any pain is minimal.

How Often Are NAD+ Injections Typically Used?

The recommended protocol is to administer one dose daily for three consecutive days, followed by a maintenance phase of dosing every other day. If continuing long-term, cycling the treatment, such as three months on followed by three months off, is advised to support optimal results and minimise potential side effects.

How Quickly Do NAD+ Injections Work?

NAD+ injections begin working immediately upon administration; however, the timing of potential benefits can vary between individuals.

Some users may feel an instant boost in energy, while others might notice improvements within 24 to 48 hours. Cumulative effects and more significant benefits typically develop over days or weeks of consistent use. It’s important to note that some individuals may not feel any noticeable effects at all, as the response can depend on factors such as lifestyle, age, and medical history.

Can I Administer NAD+ Injections Myself?

Yes, NAD+ AT HOME injection kits are designed to be used at home. You can administer it yourself or have a trusted person help.

NAD+ Injections at NAD+ AT HOME

If you’d like to learn more about NAD+ supplements, NAD+ AT HOME provides safe and convenient solutions and is available to answer any further questions you may have.