Being health-conscious has become common, as well as an open-mindedness to trying supplements and specialist foods to improve physical and mental wellbeing.
An example of their popularity can be seen in NAD+ and Creatine supplements.
We’re going to take a closer look at how these supplements work together, and whether they help support an active lifestyle.
Can You Take NAD+ and Creatine Together?
Yes, you can take NAD+ and Creatine together.
There is currently no solid and established evidence suggesting that NAD+ and creatine should not be taken together by healthy adults.
NAD+ and Creatine work through different, but complementary, biological mechanisms. Even though they can be taken together, many people take some separately to achieve different wellness goals.
Supplements have become more popular in recent years. Whilst they may be useful for wellness goals, anyone with a medical condition or taking prescription medication should consult their doctor before starting new supplements.
Qu'est-ce que le NAD+ ?
NAD+ (nicotinamide adenine dinucleotide) is a naturally occurring coenzyme found in every cell in your body.
It is involved in numerous bodily processes, but most importantly has an essential role in cellular energy production and normal metabolic processes. It works by helping your body turn what you ingest into fuel and support mitochondrial functioning.
No matter what, NAD+ levels in your body decline as you age. In fact, your natural NAD+ levels drop by around 50% by the time you reach middle age.
NAD+ can support:
- Cell energy
- DNA repair and cell regeneration
- Metabolism
- Managing oxidative stress and inflammation
How Creatine Works
Creatine is naturally occurring and produced in the kidneys, liver and pancreas but is found in the muscles and acts as a natural source of energy, helping them flex.
It is often helpful during short bursts of high-intensity activity because it recycles ATP (adenosine triphosphate), the main energy source for cells.
Commonly used in sports nutrition supplements, it supports muscle growth and minimises age-related muscle deterioration. Creatine also may support muscle strength and increase muscle mass.
Active users and athletes use Creatine to support exercise performance, strength and recovery as part of a training regimen.
NAD+ and Creatine – What’s The Difference?
NAD+ helps to drive ATP production for constant usage, while creatine is involved in recycling used cellular energy (ADP) back into ATP, which replenishes energy
You could look at it as NAD+ is the foundation for energy production in the body. In times of high energy demand, Creatine is the compound that can help maintain energy levels through the recycling of ATP.
Both of them are related to energy metabolism, performing different biological roles but helping towards the same goal:
Supporting your bodily energy.
Are There Any Known Interactions?
The interaction between NAD+ and Creatine is a genuine gap in the current science. But so far, there is no established evidence of an adverse interaction between NAD+ and creatine.
However, one study from 2021 suggested that combining Creatine and NAD may protect cells from stress.
Supplement Stacking
If you want to take supplements together, this is known as stacking. If you stack supplements without understanding individual needs, it can lead to poor absorption, lessening any impact, potential toxicity and unwanted interactions.
To limit the risk of any negative interactions occurring, you should always follow the supplement manufacturer guidance and recommended serving sizes.
Who Might Consider Taking Both?
Many people might find it beneficial to take both NAD+ and Creatine supplements to help support their health:
- Active adults – Those who exercise regularly and are generally active will benefit from how these supplements could support energy levels, exercise performance, and recovery.
- Regular gym users – People who frequent gyms rely on strength, having energy and recovering well to support their workouts.
- Healthy ageing enthusiasts – Muscles and energy levels decrease as we age. NAD+ and Creatine may support cellular function, energy metabolism, and overall wellbeing that naturally decrease.
- Demanding jobs – Those with busy schedules will benefit from supplements that support their overall health in a convenient and non-invasive way.
- People following nutrition and exercise programmes – Supplements can be an added tool, working alongside nutrition and exercise to aid those who are looking to lose weight and training for a specific active event.
Supplements may support healthy living, but your active lifestyle should be based around a balanced diet, regular exercise and sufficient sleep.
Best Practices for Taking NAD+ and Creatine
Whilst there seems to be no dangerous interactions between NAD+ and Creatine, it’s important to be as safe as possible.
- Take recommended doses
- Keep on top of hydration, especially with creatine (promotes muscle growth)
- Be patient – results won’t occur overnight
- Buy supplements from a reputable supplier
- Keep an eye on how your body reacts and stop if you notice any sudden changes
- Always consult a healthcare professional for more advice
Learn More About NAD+ and Creatine Support
So, can you take NAD and creatine together?
Although supplements shouldn’t replace your nutrition, exercise and sleep habits, for those who lead active lifestyles, in recommended doses, the combination supports better performance and health.
If you’re still unsure about the benefits of NAD, check out our range of NAD+ products et educational resources.